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Article

The Causal Role of Circulating Inflammatory Cytokines in Brain Tumors: Insights from Genetic Epidemiology.

Immunological investigations - 1 Jul 2026

Qi Teng, Yao Lingjun, Wen Zheyu, Zhou Xiaorui, Zhao Hanqing, He Jiazhen, Hu Jing

Abstract excerpt

BACKGROUND: Previous studies indicate associations between inflammatory cytokines and glioma, meningioma, and astrocytoma. METHODS: We conducted two-sample Mendelian randomization with genetic data for tumors from FinnGen R10 and cytokine data from GWAS. Primary analysis used inverse variance weighting, supplemented by sensitivity analyses including weighted median, simple mode, weighted mode, and MR-Egger....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41869993
DOI: 10.1080/08820139.2026.2647055

Genes

CD5
FGF21
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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