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Article

Common variation in genes related to innate immunity and risk of adult glioma.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 May 2009

Rajaraman Preetha, Brenner Alina V, Butler Mary Ann, Wang Sophia S, Pfeiffer Ruth M, Ruder Avima M, Linet Martha S, Yeager Meredith, Wang Zhaoming, Orr Nick, Fine Howard A, Kwon Deukwoo, Thomas Gilles, Rothman Nathaniel, Inskip Peter D, Chanock Stephen J

Abstract excerpt

Current evidence suggests that immune system alterations contribute to the etiology of adult glioma, the most common adult brain tumor. Although previous studies have focused on variation in candidate genes in the adaptive immune system, the innate immune system has emerged as a critical avenue for research given its known link with carcinogenesis. To identify genetic markers in pathways critical to innate...

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Identifiers

PMID: 19423540
DOI: 10.1158/1055-9965.EPI-08-1041
PMCID: PMC2771723

Genes

SELP
ALOX5
IRAK3
ITGB2
NCF2
NFKB1
SERPINI1
SOD1
STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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