Article

Genetic Variation and Regulation of MICA Alters Natural Killer Cell-Mediated Immunosurveillance in Early-Onset Colorectal Cancer

2024-09-26

Abstract excerpt

The incidence of colorectal cancer (CRC) among individuals under age 50, or early-onset CRC (EOCRC), has been rising over the past few decades for unclear reasons, and the etiology of the disease remains largely unknown. Known genetic risk factors do not explain this increase, pointing to possible environmental and as-yet unidentified genetic contributors and their interactions. Previous research linked genetic va...

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Literature Corpus work: f59699fe-9175-5bed-96ee-7b0ec5fa2c68
DOI: 10.1101/2024.09.22.24314127

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