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Article

Prognostic relevance of genetic variants involved in immune checkpoints in patients with colorectal cancer.

Journal of cancer research and clinical oncology - 1 Aug 2016

Yoon Shinkyo, Kang Byung Woog, Park Su Yeon, Kim Hye Jin, Park Jun Seok, Choi Gyu Seog, Kim Jong Gwang

Abstract excerpt

PURPOSE: Genetic polymorphisms in genes involved in the immune response are already known to affect the anti-tumor immune response. This study systematically investigated the association of 14 functional SNPs in a panel of 7 genes (CCL2, CCR2, NT5E, IDO1, LAG3, PDL1, and PDCD1) involved in immune response checkpoints with the survival outcomes of Korean patients with colorectal cancer (CRC). METHODS: The genomic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27339628
DOI: 10.1007/s00432-016-2196-2

Genes

CCL2
PDCD1
CCR2
IDO1
LAG3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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