Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cloning and characterization of a novel human BRMS1 transcript variant in hepatocellular carcinoma cells.

Cancer letters - 1 Sept 2013

Wu Jun, Wang Yingming, Qiao Xiaojing, Saiyin Hexige, Zhao Shenan, Qiao Shouyi, Wu Yanhua

Abstract excerpt

Breast cancer metastasis suppressor 1 (BRMS1) is able to suppress tumor metastasis without affecting primary tumor growth in various cancers. Here, we report a novel transcript variant of human BRMS1, termed BRMS1.vh. BRMS1.vh is identical to the major BRMS1 variant (BRMS1.v1) except for missing base pairs 683-775, encoding a 215-amino acid protein lacking a functional nuclear localization sequence. Expression of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alternative Splicing
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Reporter

Share to Liver Neoplasms

Share to Mice, Inbred BALB C

Share to Mice, Nude

Share to NF-kappa B

Share to Tumor Burden

Source

Identifiers

PMID: 23643861
DOI: 10.1016/j.canlet.2013.04.030

Genes

BRMS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cloning and characterization of a novel human BRMS1 transcript variant in hepatocellular carcinoma cells.PMID 23643861Read ↗

Breast cancer metastasis suppressor gene, breast cancer metastasis suppressor 1, may be associated with clinicopathological features of breast cancer.Semantic proximity Read ↗

Transcriptomic characterization of hepatocellular carcinoma with CTNNB1 mutation.Semantic proximity Read ↗

A germline SNP in BRMS1 predisposes patients with lung adenocarcinoma to metastasis and can be ameliorated by targeting c-fos.Semantic proximity Read ↗

B-cell translocation gene 1 serves as a novel prognostic indicator of hepatocellular carcinomaSemantic proximity Read ↗

CHD1L: a novel oncogeneSemantic proximity Read ↗

Two BRM promoter polymorphisms predict poor survival in patients with hepatocellular carcinoma.Semantic proximity Read ↗

Identification and characterization of the murine ortholog <i>(brms1)</i> of breast‐cancer metastasis suppressor 1 <i>(BRMS1)</i>Semantic proximity Read ↗

A novel XBP1 variant is highly enriched in cancer tissues and is specifically required for cancer cell survival.Semantic proximity Read ↗

Alterations of the SWI/SNF chromatin remodelling subunit-BRG1 and BRM in hepatocellular carcinoma.Semantic proximity Read ↗

Insertion/deletion polymorphisms in the promoter region of BRM contribute to risk of hepatocellular carcinoma in Chinese populations.Semantic proximity Read ↗

The pVHL172 isoform is not a tumor suppressor and up-regulates a subset of pro-tumorigenic genes includingTGFB1andMMP13Semantic proximity Read ↗

Overexpression and role of the ATPase and putative DNA helicase RuvB-like 2 in human hepatocellular carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.