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The pVHL172 isoform is not a tumor suppressor and up-regulates a subset of pro-tumorigenic genes includingTGFB1andMMP13
6 Jun 2017
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// Pauline Hascoet 1 , Franck Chesnel 1 , Florence Jouan 1, ** , Cathy Le Goff 1 , Anne Couturier 1 , Eric Darrigrand 2 , Fabrice Mahe 2 , Nathalie Rioux-Leclercq 3 , Xavier Le Goff 1, * and Yannick Arlot-Bonnemains 1, * 1 CNRS, UMR 6290 IGDR, Université Rennes 1, BIOSIT, Rennes, France 2 IRMAR, Université Rennes 1, Rennes, France 3 CHU Rennes, Service d’Anatomo-Pathologie, Rennes, France * Co-last authors **...
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