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Article

High frequency of NAD(P)H:quinone oxidoreductase 1 (NQO1) C(609)T germline polymorphism in MDS/AML with trisomy 8.

Leukemia research - 1 Jul 2013

Zachaki Sophia, Stavropoulou Chrysa, Koromila Theodora, Manola Kalliopi N, Kalomoiraki Marina, Daraki Aggeliki, Koumbi Daphne, Athanasiadou Anastasia, Kanavakis Emmanuel, Kollia Panagoula, Sambani Constantina

Abstract excerpt

The NQO1 C(609)T germline polymorphism resulting in a lowering of enzyme activity may confer susceptibility to MDS. To assess this association, we performed a case-control study including 330 Greek patients with de novo MDS and 416 healthy donors, using a Real-Time PCR genotyping method. Focusing on cytogenetic aberrations most commonly found in MDS, we retrospectively genotyped 566 MDS/AML patients carrying...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23643325
DOI: 10.1016/j.leukres.2013.04.015

Genes

NQO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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High frequency of NAD(P)H:quinone oxidoreductase 1 (NQO1) C(609)T germline polymorphism in MDS/AML with trisomy 8.PMID 23643325Read ↗

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