Article
Effects of the NQO1 609C>T polymorphism on leukemia susceptibility: evidence from a meta-analysis.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013
Han Fei-Fei, Guo Chang-Long, Gong Li-Li, Jin Zhu, Liu Li-Hong
Abstract excerpt
A functional polymorphism in the NQO1 gene, featuring a 609C>T substitution,leading to proline to serine amino-acid and enzyme activity changes, has been implicated in cancer risk. However, individually published investigations showed inconclusive results, especially for leukemia. In this study,...
Topics
- Case-Control Studies
- Genetic Predisposition to Disease
- Humans
- Leukemia
- NAD(P)H Dehydrogenase (Quinone)
- Polymorphism, Genetic
- Prognosis