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Article

Partial agonism of taurine at gamma-containing native and recombinant GABAA receptors.

PloS one - 1 Jan 2013

Kletke Olaf, Gisselmann Guenter, May Andrea, Hatt Hanns, Sergeeva Olga A

Abstract excerpt

Taurine is a semi-essential sulfonic acid found at high concentrations in plasma and mammalian tissues which regulates osmolarity, ion channel activity and glucose homeostasis. The structural requirements of GABAA-receptors (GABAAR) gated by taurine are not yet known. We determined taurine potency and efficacy relative to GABA at different types of recombinant GABAAR occurring in central histaminergic neurons of...

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Identifiers

PMID: 23637894
DOI: 10.1371/journal.pone.0061733
PMCID: PMC3640040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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