Article
Trans-activation between 7TM domains: implication in heterodimeric GABAB receptor activation.
The EMBO journal - 5 Jan 2011
Monnier Carine, Tu Haijun, Bourrier Emmanuel, Vol Claire, Lamarque Laurent, Trinquet Eric, Pin Jean-Philippe, Rondard Philippe
Abstract excerpt
Seven-transmembrane domain (7TM) receptors have important functions in cell-cell communication and can assemble into dimers or oligomers. Such complexes may allow specific functional cross-talk through trans-activation of interacting 7TMs, but this hypothesis requires further validation. Herein,...
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