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Article

Tyrosine phosphorylation of GABAA receptor γ2-subunit regulates tonic and phasic inhibition in the thalamus.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 31 Jul 2013

Nani Francesca, Bright Damian P, Revilla-Sanchez Raquel, Tretter Verena, Moss Stephen J, Smart Trevor G

Abstract excerpt

GABA-mediated tonic and phasic inhibition of thalamic relay neurons of the dorsal lateral geniculate nucleus (dLGN) was studied after ablating tyrosine (Y) phosphorylation of receptor γ2-subunits. As phosphorylation of γ2 Y365 and Y367 reduces receptor internalization, to understand their importa...

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Identifiers

PMID: 23904608
DOI: 10.1523/JNEUROSCI.0388-13.2013
PMCID: PMC4400286

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23904608-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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