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Article

Development of a Robust Mammalian Cell-based Assay for Studying Recombinant α4 β1/3 δ GABAA Receptor Subtypes.

Basic & clinical pharmacology & toxicology - 1 Aug 2017

Falk-Petersen Christina B, Søgaard Rikke, Madsen Kenneth L, Klein Anders B, Frølund Bente, Wellendorph Petrine

Abstract excerpt

δ-Containing GABAA receptors are located extrasynaptically and mediate tonic inhibition. Their involvement in brain physiology positions them as interesting drug targets. There is thus a continued interest in establishing reliable recombinant expression systems for δ-containing GABAA receptors. Inconveniently, the recombinant expression of especially α4 β1/3 δ receptors has been found to be notoriously difficult,...

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PMID: 28299900
DOI: 10.1111/bcpt.12778

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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