Article
Ablation of ghrelin O-acyltransferase does not improve glucose intolerance or body adiposity in mice on a leptin-deficient ob/ob background.
PloS one - 1 Jan 2013
Kirchner Henriette, Heppner Kristy M, Holland Jenna, Kabra Dhiraj, Tschöp Matthias H, Pfluger Paul T
Abstract excerpt
Type 2 Diabetes is a global health burden and based on current estimates will become an even larger problem in the future. Developing new strategies to prevent and treat diabetes is a scientific challenge of high priority. The stomach hormone ghrelin has been associated with playing a role in the regulation of glucose homeostasis. However, its precise mechanism and impact on whole glucose metabolism remains to be...
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