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Article

Genetic variation of the ghrelin activator gene ghrelin O-acyltransferase (GOAT) is associated with anorexia nervosa.

Journal of psychiatric research - 1 May 2011

Müller Timo D, Tschöp Matthias H, Jarick Ivonne, Ehrlich Stefan, Scherag Susann, Herpertz-Dahlmann Beate, Zipfel Stefan, Herzog Wolfgang, de Zwaan Martina, Burghardt Roland, Fleischhaker Christian, Klampfl Karin, Wewetzer Christoph, Herpertz Stephan, Zeeck Almut, Tagay Sefik, Burgmer Markus, Pfluger Paul T, Scherag André, Hebebrand Johannes, Hinney Anke

Abstract excerpt

The gastrointestinal peptide hormone ghrelin promotes food intake and increases body weight and adiposity through activation of the growth hormone secretagogue receptor (GHSR1a). To promote its biological action ghrelin is acylated at its serine 3 residue by the recently discovered ghrelin O-acyl...

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Source

Identifiers

PMID: 21035823
DOI: 10.1016/j.jpsychires.2010.10.001

Genes

MBOAT4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21035823-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Genetic variation of the ghrelin activator gene ghrelin O-acyltransferase (GOAT) is associated with anorexia nervosa.PMID 21035823Read ↗

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