Article
Physiological role of ghrelin as revealed by the ghrelin and GOAT knockout mice.
Peptides - 1 Nov 2011
Kang Kihwa, Zmuda Erik, Sleeman Mark W
Abstract excerpt
Ghrelin is a gastric hormone that has been shown to regulate food intake and energy metabolism. One unique feature of ghrelin is that its activity is regulated post transcriptionally by ghrelin O-acyltransferase (GOAT) through the addition of fatty acid to the serine residue in the N terminal region. Despite much biochemical characterization, to date no other proteins have been shown to be specifically...
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