Article
Transgenic mice overexpressing ghrelin or ghrelin analog.
Methods in enzymology - 1 Jan 2012
Ariyasu Hiroyuki, Yamada Go, Iwakura Hiroshi, Akamizu Takashi, Kangawa Kenji, Nakao Kazuwa
Abstract excerpt
To understand the chronic effects of ghrelin, genetically engineered mouse models would be useful. Early studies, however, suggested that it was challenging to generate ghrelin gain-of-activity models by standard procedures. Although several groups have been trying to generate transgenic (Tg) mic...
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