Article
Multiplex B cell characterization in blood, lymph nodes, and tumors from patients with malignancies.
Journal of immunology (Baltimore, Md. : 1950) - 1 Jun 2013
Zirakzadeh A Ali, Marits Per, Sherif Amir, Winqvist Ola
Abstract excerpt
B lymphocytes contribute to immune surveillance, by tumor-specific Abs and Ag presentation to T lymphocytes, but are insufficiently studied in humans. In this article, we report a flow cytometric investigation of B lymphocyte subpopulations in blood, lymph nodes (LNs), and malignant tissues from 20 patients operated on because of advanced solid tumors. The CD19(+) compartment in peripheral blood was essentially...
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