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Phenotypic characterization and function of tumor infiltrating and peripheral B cells in cancer patients.

Methods in cell biology - 1 Jan 2026

Rosado M Manuela, Frisullo Giuseppe, Campo Giulia, Petrella Miriam, Nisticò Paola

Abstract excerpt

Lymphocyte characterization is primarily based on the differential expression of surface markers. In this context multiparametric flow-cytometry analysis (FACS) is an exceptional technique that not only allows the identification of lymphocyte subsets but can also be used to evaluate cell function, activation and proliferation. Owed the recent observation that B cells play key roles in anti-tumour immune responses...

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Identifiers

PMID: 41688152
DOI: 10.1016/bs.mcb.2025.11.001

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