Article

Identification of clonally expanded Tγδ populations during CAR-T cell therapy

2024-09-02

Abstract excerpt

Anti-CD19 Chimeric Antigen Receptor (CAR-) T cell therapies have shown promise for treating B cell malignancies, but the clinical outcome is influenced by both the CAR-T product and the patient’s immune system. The role of Tγδ cells in the context of CAR-T cell therapy remains poorly understood. This study investigates the clonal expansion, transcriptional heterogeneity, and migration profiles of Tgd cells in pati...

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Literature Corpus work: 3b40a1b1-f634-5eb2-a506-422e8caa5d7c
DOI: 10.22541/au.172525996.65227889/v1

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