Article
Next-generation sequencing reveals high concordance of recurrent somatic alterations between primary tumor and metastases from patients with non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Jun 2013
Vignot Stéphane, Frampton Garrett M, Soria Jean-Charles, Yelensky Roman, Commo Frédéric, Brambilla Christian, Palmer Gary, Moro-Sibilot Denis, Ross Jeffrey S, Cronin Maureen T, André Fabrice, Stephens Philip J, Lazar Vladimir, Miller Vincent A, Brambilla Elisabeth
Abstract excerpt
PURPOSE: Characterization of the genomic changes that drive an individual patient's disease is critical in management of many cancers. In patients with non-small-cell lung cancer (NSCLC), obtaining tumor samples of sufficient size for genomic profiling on recurrence is often challenging. We under...
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