Article

Genomic profiling implicates candidate genes and mutagenic pathways driving lung cancer recurrence

2026-01-01

Abstract excerpt

<h4>ABSTRACT</h4> Lung cancer remains the leading cause of cancer-related deaths worldwide, with tumor recurrence a major contributor to its high mortality. The genetic and molecular mechanisms of recurrence remain poorly understood. Using whole-exome sequencing of 155 primary non-small cell lung cancers, we studied the mutational landscape and driver alterations associated with recurrence. Primary tumors that de...

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Literature Corpus work: 036a05a2-a810-51da-9e63-329d9ea703a0
DOI: 10.64898/2025.12.24.25342926

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