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Article

Temporal genomic heterogeneity guiding individualized therapy in recurrent non-small cell lung cancer

12 Jul 2023

Abstract excerpt

Introduction: Despite the benefit of adjuvant systemic therapy for patients with resected non-small cell lung cancer (NSCLC), the risk of postoperative recurrence remains high. Our objective was to characterize temporal genetic heterogeneity between primary resected and recurrent tumors, and its impact on treatment outcomes. Methods: In this study, next-generation sequencing (NGS) testing was performed on tissue...

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PMID: 37503313
DOI: 10.3389/fonc.2023.1116809

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