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Article

Epidermal growth factor-induced cellular invasion requires sphingosine-1-phosphate/sphingosine-1-phosphate 2 receptor-mediated ezrin activation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Aug 2013

Orr Gandy K Alexa, Adada Mohamad, Canals Daniel, Carroll Brittany, Roddy Patrick, Hannun Yusuf A, Obeid Lina M

Abstract excerpt

Ezrin, radixin, and moesin (ERM) proteins link cortical actin to the plasma membrane and coordinate cellular events that require cytoskeletal rearrangement, including cell division, migration, and invasion. While ERM proteins are involved in many important cellular events, the mechanisms regulating their function are not completely understood. Our laboratory previously identified reciprocal roles for the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23629860
DOI: 10.1096/fj.13-228460
PMCID: PMC3714586

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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