ERM proteins in cancer progression

doi:10.1242/jcs.133108

Article

ERM proteins in cancer progression

13 Jan 2014

Abstract excerpt

Members of the ezrin-radixin-moesin (ERM) family of proteins are involved in multiple aspects of cell migration by acting both as crosslinkers between the membrane, receptors and the actin cytoskeleton, and as regulators of signalling molecules that are implicated in cell adhesion, cell polarity and migration. Increasing evidence suggests that the regulation of cell signalling and the cytoskeleton by ERM proteins...

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