Article
The Janus-faced role of ezrin in "linking" cells to either normal or metastatic phenotype.
International journal of cancer - 15 Nov 2009
Brambilla Daria, Fais Stefano
Abstract excerpt
In the majority of eukaryotic cells, the ezrin, radixin and moesin (ERM) proteins are involved in many physiologic functions including regulation of actin cytoskeleton, control of cell shape, adhesion, motility and modulation of signal transduction pathways. In a previous study, we used a dominant negative ezrin-mutant to address ezrin involvement in remodeling of actin cytoskeleton and subsequently we depicted...
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