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Ezrin Mediates Invasion and Metastasis in Tumorigenesis: A Review

10 Nov 2020

Abstract excerpt

Ezrin, as encoded by the EZR gene, is a member of the Ezrin/Radixin/Moesin (ERM) family. The ERM family includes three highly related actin filament binding proteins, Ezrin, Radixin, and Moesin. These three members share similar structural properties containing an N-terminal domain named FERM, a central helical linker region, and a C-terminal domain that mediates the interaction with F-actin. Ezrin protein is...

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Identifiers

PMID: 33240887
DOI: 10.3389/fcell.2020.588801

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