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Article

Asthma severity, polymorphisms in 20p13 and their interaction with tobacco smoke exposure.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Feb 2013

Bukvic Blazenka Kljaic, Blekic Mario, Simpson Angela, Marinho Susana, Curtin John A, Hankinson Jenny, Aberle Neda, Custovic Adnan

Abstract excerpt

BACKGROUND: We investigated the association between genetic variation in chromosomal region 20p13-p12 (ADAM33 and flanking genes ATRN, GFRA4, SIGLEC1 and HSPA12B) and asthma. Amongst asthmatics, we then investigated the association between genetic variants and asthma severity. We evaluated the effect of environmental tobacco smoke (ETS) exposure in the context of genetic variants. METHODS: In a case-control...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23331525
DOI: 10.1111/pai.12019

Genes

ADAM33
SIGLEC1
ARTN
ATRN
GFRA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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