Cat exposure in early life decreases asthma risk from the 17q21 high-risk variant.

doi:10.1016/j.jaci.2017.07.044

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Article

Cat exposure in early life decreases asthma risk from the 17q21 high-risk variant.

The Journal of allergy and clinical immunology - 1 May 2018

Stokholm Jakob, Chawes Bo L, Vissing Nadja, Bønnelykke Klaus, Bisgaard Hans

Abstract excerpt

BACKGROUND: Early-life exposure to cats and dogs has shown diverging associations with childhood asthma risk, and gene-environment interaction is one possible explanation. OBJECTIVES: We investigated interactions between cat and dog exposure and single nucleotide polymorphism rs7216389 variants in the chromosome 17q21 locus, the strongest known genetic risk factor for childhood asthma. METHODS: Genotyping was...

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Identifiers

PMID: 29102067
DOI: 10.1016/j.jaci.2017.07.044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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