Article
Differential expression of imprinted genes in normal and IUGR human placentas.
Epigenetics - 16 May 2009
Diplas Andreas I, Lambertini Luca, Lee Men-Jean, Sperling Rhoda, Lee Yin Leng, Wetmur James, Chen Jia
Abstract excerpt
Genomic imprinting refers to silencing of one parental allele in the zygotes of gametes depending upon the parent of origin. Loss of imprinting (LOI) is the gain of function from the silent allele that can have a maximum effect of doubling the gene dosage. LOI may play a significant role in the e...
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