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Article

Tissue-specific DNA methylation profiles in newborns

31 May 2013

Abstract excerpt

BACKGROUND: Epidemiological studies demonstrate that foetal growth restriction and low birth weight affect long-term health. Derangements in tissue-specific epigenetic programming of foetal and placental tissues are a suggested underlying mechanism of which DNA methylation is best understood. DNA methylation has been mostly investigated in DNA from white blood cells. To improve baseline understanding of...

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PMID: 23724794
DOI: 10.1186/1868-7083-5-8

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