Article
Establishment of functional imprinting of the H19 gene in human developing placentae.
Nature genetics - 1 Jul 1995
Jinno Y, Ikeda Y, Yun K, Maw M, Masuzaki H, Fukuda H, Inuzuka K, Fujishita A, Ohtani Y, Okimoto T
Abstract excerpt
We have found that the imprinted H19 gene can be expressed either biallelically or monoallelically in the developing human placentae. H19 biallelic expression is confined to the placenta until 10 weeks of gestation, after which it becomes exclusively maternal, and does not affect allele-specifici...
Topics
- Alleles
- Base Sequence
- DNA
- DNA Primers
- Female
- Gene Expression Regulation, Developmental
- Genomic Imprinting
- Humans
- In Situ Hybridization
- Insulin-Like Growth Factor II
- Methylation
- Molecular Sequence Data
- Muscle Proteins
- Placenta
- Placentation
- Polymerase Chain Reaction
- Pregnancy
- Promoter Regions, Genetic