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Article

Altered gene expression and methylation of the human chromosome 11 imprinted region in small for gestational age (SGA) placentae.

Developmental biology - 1 Aug 2008

Guo Lin, Choufani Sanaa, Ferreira Jose, Smith Adam, Chitayat David, Shuman Cheryl, Uxa Ruchita, Keating Sarah, Kingdom John, Weksberg Rosanna

Abstract excerpt

Imprinted genes are known to be crucial for placental development and fetal growth in mammals, but no primary epigenetic abnormality in placenta has been documented to compromise human fetal growth. Imprinted genes demonstrate parent-of-origin-specific allelic expression that is epigenetically regulated i.e. extrinsic to the primary DNA sequence. To undertake an epigenetic analysis of poor fetal growth in...

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Source

Identifiers

PMID: 18550048
DOI: 10.1016/j.ydbio.2008.04.025

Genes

IGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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