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Article

Effects of a Polymorphism of the Neuronal Amino Acid Transporter SLC6A15 Gene on Structural Integrity of White Matter Tracts in Major Depressive Disorder.

PloS one - 1 Jan 2016

Choi Sunyoung, Han Kyu-Man, Kang June, Won Eunsoo, Chang Hun Soo, Tae Woo Suk, Son Kyu Ri, Kim Su-Jin, Lee Min-Soo, Ham Byung-Joo

Abstract excerpt

BACKGROUND: The SLC6A15 gene has been identified as a novel candidate gene for major depressive disorder (MDD). It is presumed to be involved in the pathophysiology of MDD through regulation of glutamate transmission in the brain. However, the involvement of this gene in microstructural changes in white matter (WM) tracts remains unclear. We aimed to investigate the influence of a polymorphism of this gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27723767
DOI: 10.1371/journal.pone.0164301
PMCID: PMC5056691

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