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Article

TERRA, hnRNP A1, and DNA-PKcs Interactions at Human Telomeres

1 Jan 2013

Abstract excerpt

Maintenance of telomeres, repetitive elements at eukaryotic chromosomal termini, and the end-capping structure and function they provide, are imperative for preserving genome integrity and stability. The discovery that telomeres are transcribed into telomere repeat containing RNA (TERRA) has revolutionized our view of this repetitive, rather unappreciated region of the genome. We have previously shown that the...

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Identifiers

PMID: 23616949
DOI: 10.3389/fonc.2013.00091

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TERRA, hnRNP A1, and DNA-PKcs Interactions at Human TelomeresPMID 23616949Read ↗

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Telomeric repeat-containing RNA TERRA: a noncoding RNA connecting telomere biology to genome integritySemantic proximity Read ↗

TERRA long noncoding RNA: At the interphase of telomere damage, rescue and signalingSemantic proximity Read ↗

BRCA1 binds TERRA RNA and suppresses R-Loop-based telomeric DNA damage.Semantic proximity Read ↗

Live-cell imaging reveals the dynamics and function of single-telomere TERRA molecules in cancer cellsSemantic proximity Read ↗

Regulated expression of the lncRNA TERRA and its impact on telomere biology.Semantic proximity Read ↗

Role of TERRA in the Regulation of Telomere LengthSemantic proximity Read ↗

Telomeric Noncoding RNA TERRA Is Induced by Telomere Shortening to Nucleate Telomerase Molecules at Short TelomeresSemantic proximity Read ↗

The THO complex counteracts TERRA R-loop-mediated telomere fragility in telomerase+ cells and telomeric recombination in ALT+ cellsSemantic proximity Read ↗

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