Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PHD2 regulates arteriogenic macrophages through TIE2 signalling.

EMBO molecular medicine - 1 Jun 2013

Hamm Alexander, Veschini Lorenzo, Takeda Yukiji, Costa Sandra, Delamarre Estelle, Squadrito Mario Leonardo, Henze Anne-Theres, Wenes Mathias, Serneels Jens, Pucci Ferdinando, Roncal Carmen, Anisimov Andrey, Alitalo Kari, De Palma Michele, Mazzone Massimiliano

Abstract excerpt

Occlusion of the main arterial route redirects blood flow to the collateral circulation. We previously reported that macrophages genetically modified to express low levels of prolyl hydroxylase domain protein 2 (PHD2) display an arteriogenic phenotype, which promotes the formation of collateral v...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiopoietin-1
Share to Angiopoietin-2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Down-Regulation

Share to Gene Silencing

Share to Hypoxia-Inducible Factor-Proline Dioxygenases

Share to Ischemia

Share to Procollagen-Proline Dioxygenase

Share to Receptor, TIE-2

Source

Open in PubMed Open full text

Identifiers

PMID: 23616286
DOI: 10.1002/emmm.201302695
PMCID: PMC3779447

Genes

ANG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23616286-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PHD2 regulates arteriogenic macrophages through TIE2 signalling.PMID 23616286Read ↗

Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis.Semantic proximity Read ↗

Blood vessel control of macrophage maturation promotes arteriogenesis in ischemia.Semantic proximity Read ↗

ApoA-I Nanotherapy Rescues Postischemic Vascular Maladaptation by Modulating Endothelial Cell and Macrophage Phenotypes in Type 2 Diabetic Mice.Semantic proximity Read ↗

Role of macrophage-derived hypoxia-inducible factor (HIF)-1α as a mediator of vascular remodelling.Semantic proximity Read ↗

Myeloid Drp1 Deficiency Limits Revascularization in Ischemic Muscles via Inflammatory Macrophage Polarization and Metabolic ReprogramingSemantic proximity Read ↗

Inflammatory macrophages drive smooth muscle dedifferentiation via YAP signaling in murine deep vein thrombosisSemantic proximity Read ↗

The temporal and spatial distribution of macrophage subpopulations during arteriogenesis.Semantic proximity Read ↗

The angiopoietin receptor Tie2 is atheroprotective in arterial endotheliumSemantic proximity Read ↗

Galectin-2 induces a proinflammatory, anti-arteriogenic phenotype in monocytes and macrophages.Semantic proximity Read ↗

Epigenetic regulation of the PGE2 pathway modulates macrophage phenotype in normal and pathologic wound repair.Semantic proximity Read ↗

BACH1 deficiency prevents neointima formation and maintains the differentiated phenotype of vascular smooth muscle cells by regulating chromatin accessibility.Semantic proximity Read ↗

AMP-Activated Protein Kinase α1 in Macrophages Promotes Collateral Remodeling and Arteriogenesis in Mice In Vivo.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.