Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bridge-induced chromosome translocation in yeast relies upon a Rad54/Rdh54-dependent, Pol32-independent pathway.

PloS one - 1 Jan 2013

Tosato Valentina, Sidari Sabrina, Bruschi Carlo V

Abstract excerpt

While in mammalian cells the genetic determinism of chromosomal translocation remains unclear, the yeast Saccharomyces cerevisiae has become an ideal model system to generate ad hoc translocations and analyze their cellular and molecular outcome. A linear DNA cassette carrying a selectable marker flanked by perfect homologies to two chromosomes triggers a bridge-induced translocation (BIT) in budding yeast, with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Southern
Share to Chromosomes, Fungal
Share to DNA Breaks, Double-Stranded

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA-Directed DNA Polymerase

Share to DNA Helicases

Share to DNA Repair Enzymes

Share to DNA Replication

Share to Translocation, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 23613757
DOI: 10.1371/journal.pone.0060926
PMCID: PMC3629078

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bridge-induced chromosome translocation in yeast relies upon a Rad54/Rdh54-dependent, Pol32-independent pathway.PMID 23613757Read ↗

Discrete DNA integration events during Bridge-Induced Translocation generate partial chromosomal deletions and differential aneuploidy in Saccharomyces cerevisiaeSemantic proximity Read ↗

Mechanism and significance of chromosome damage repair by homologous recombinationSemantic proximity Read ↗

Different aneuploidies arise from the same bridge-induced chromosomal translocation event in Saccharomyces cerevisiae.Semantic proximity Read ↗

Saccharomyces cerevisiae rad51 mutants are defective in DNA damage-associated sister chromatid exchanges but exhibit increased rates of homology-directed translocations.Semantic proximity Read ↗

Homology-directed repair involves multiple strand invasion cycles in fission yeastSemantic proximity Read ↗

Srs2/PARI DNA helicase mediates abscission inhibition in response to chromatin bridges in yeast and human cellsSemantic proximity Read ↗

Post-translocational adaptation drives evolution through genetic selection and transcriptional shift in Saccharomyces cerevisiae.Semantic proximity Read ↗

Coordination of DNA replication and recombination activities in the maintenance of genome stabilitySemantic proximity Read ↗

Ultrafine anaphase bridges, broken DNA and illegitimate recombination induced by a replication fork barrier.Semantic proximity Read ↗

Mrc1 and Srs2 are major actors in the regulation of spontaneous crossover.Semantic proximity Read ↗

Defective break-induced replication leads to half-crossovers in Saccharomyces cerevisiae.Semantic proximity Read ↗

Physical and Genetic Assays for the Study of DNA Joint Molecules Metabolism and Multi-invasion-Induced Rearrangements in S. cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.