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Article

Defective break-induced replication leads to half-crossovers in Saccharomyces cerevisiae.

Genetics - 1 Aug 2008

Deem Angela, Barker Krista, Vanhulle Kelly, Downing Brandon, Vayl Alexandra, Malkova Anna

Abstract excerpt

Break-induced replication (BIR) is an important process of DNA metabolism that has been implicated in the restart of collapsed replication forks, as well as in various chromosomal instabilities, including loss of heterozygosity, translocations, and alternative telomere lengthening. Therefore, knowledge of how BIR is carried out and regulated is important for better understanding the maintenance of genomic...

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Identifiers

PMID: 18689895
DOI: 10.1534/genetics.108.087940
PMCID: PMC2516063

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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