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Article

Plasmacytoid dendritic cell depletion in DOCK8 deficiency: rescue of severe herpetic infections with IFN-α 2b therapy.

The Journal of allergy and clinical immunology - 1 Jun 2014

Keles Sevgi, Jabara Haifa H, Reisli Ismail, McDonald Douglas R, Barlan Isil, Hanna-Wakim Rima, Dbaibo Ghassan, Lefranc Gerard, Al-Herz Waleed, Geha Raif S, Chatila Talal A

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Share to Antiviral Agents
Share to Dendritic Cells
Share to Guanine Nucleotide Exchange Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Herpesviridae Infections

Share to Immunophenotyping

Share to Interferon-alpha

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Source

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Identifiers

PMID: 24767873
DOI: 10.1016/j.jaci.2014.03.032
PMCID: PMC4052613

Genes

DOCK8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

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Plasmacytoid dendritic cell depletion in DOCK8 deficiency: rescue of severe herpetic infections with IFN-α 2b therapy.PMID 24767873Read ↗

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Regulatory T-cell dysfunction and cutaneous exposure to Staphylococcus aureus underlie eczema in DOCK8 deficiencySemantic proximity Read ↗

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DOCK8 deficiency: clinical and immunological phenotype and treatment options - a review of 136 patients.Semantic proximity Read ↗

The extended clinical phenotype of 64 patients with dedicator of cytokinesis 8 deficiency.Semantic proximity Read ↗

CRISPR/Cas-Based Gene Editing Strategies for DOCK8 Immunodeficiency SyndromeSemantic proximity Read ↗

DOCK2-deficiency causes defects in anti-viral T cell responses and poor control of herpes simplex virus infectionSemantic proximity Read ↗

Critical immunological pathways are downregulated in APECED patient dendritic cellsSemantic proximity Read ↗

Flow cytometry biomarkers distinguish DOCK8 deficiency from severe atopic dermatitis.Semantic proximity Read ↗

DOCK8 immune deficiency as a model for primary cytoskeletal dysfunction.Semantic proximity Read ↗

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