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Article

APOBEC3 cytidine deaminases in double-strand DNA break repair and cancer promotion.

Cancer research - 15 Jun 2013

Nowarski Roni, Kotler Moshe

Abstract excerpt

High frequency of cytidine to thymidine conversions was identified in the genome of several types of cancer cells. In breast cancer cells, these mutations are clustered in long DNA regions associated with single-strand DNA (ssDNA), double-strand DNA breaks (DSB), and genomic rearrangements. The observed mutational pattern resembles the deamination signature of cytidine to uridine carried out by members of the...

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Identifiers

PMID: 23598277
DOI: 10.1158/0008-5472.CAN-13-0728
PMCID: PMC3686885

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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