Article
S100A expression and interleukin-10 polymorphisms are associated with ulcerative colitis and diarrhea predominant irritable bowel syndrome.
Digestive diseases and sciences - 1 Aug 2013
Shiotani Akiko, Kusunoki Hiroaki, Kimura Yoshiki, Ishii Mnabu, Imamura Hiroshi, Tarumi Ken-ichi, Manabe Noriaki, Kamada Tomoari, Hata Jiro, Haruma Ken
Abstract excerpt
BACKGROUND: Both ulcerative colitis (UC) and diarrhea-predominant irritable bowel syndrome (IBS-D) are associated with alterations in enteric serotonin (5-HT) signaling. AIMS: The purpose of this study was to compare the rectal and sigmoid colonic mucosal expression of S100A proteins and functional polymorphisms of the 5-HT transporter (5HTT) and interleukin-10 genes in patients with IBS-D or UC with healthy...
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