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Article

Serotonin transporter gene promoter region polymorphisms and serotonin transporter expression in the colonic mucosa of irritable bowel syndrome patients.

Neurogastroenterology and motility - 1 Jun 2012

Wang Y M, Chang Y, Chang Y Y, Cheng J, Li J, Wang T, Zhang Q Y, Liang D C, Sun B, Wang B M

Abstract excerpt

BACKGROUND: The role of serotonin transporter (SERT) gene polymorphism in irritable bowel syndrome (IBS) has been demonstrated. However, the expression of SERT mRNA and proteins in the colonic mucosa with different 5-HTT gene-linked polymorphic region (5-HTTLPR) genotypes remains unknown. We examined SERT mRNA and protein levels in colon biopsies from patients with different 5-HTTLPR genotypes and evaluated the...

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Source

Identifiers

PMID: 22435794
DOI: 10.1111/j.1365-2982.2012.01902.x

Genes

HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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