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Article

Serotonin Transporter Gene Polymorphism in Irritable Bowel Syndrome

1 Jul 2002

Abstract excerpt

OBJECTIVES: Serotonin is a key mediator of intestinal peristalsis, and after it is secreted, it is effectively cleansed from the neuronal gap by means of a high affinity substance called serotonin transporter (SERT), which depends on the Na+ and Cl- ions localized in the presynaptic neuronal membranes. The aim of this study was to investigate SERT polymorphism in patients with irritable bowel syndrome (IBS)....

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PMID: 12135035
DOI: 10.1111/j.1572-0241.2002.05841.x

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