Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Influence of the serotonin transporter 5HTTLPR polymorphism on symptom severity in irritable bowel syndrome.

PloS one - 1 Jan 2013

Colucci Rocchina, Gambaccini Dario, Ghisu Narcisa, Rossi Giuseppe, Costa Francesco, Tuccori Marco, De Bortoli Nicola, Fornai Matteo, Antonioli Luca, Ricchiuti Angelo, Mumolo Maria Gloria, Marchi Santino, Blandizzi Corrado, Bellini Massimo

Abstract excerpt

5HTTLPR polymorphism of serotonin transporter yields short (S) and long (L) alleles. SS and LS genotypes are associated with reduced expression of serotonin transporter. This cross-sectional study investigated the association of 5HTTLPR with symptom severity of irritable bowel syndrome (IBS). Patients with IBS (Rome III) and healthy controls were included. Genomic DNA was extracted from saliva, and 5HTTLPR...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genotype
Share to Irritable Bowel Syndrome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Genetic

Share to Serotonin Plasma Membrane Transport Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 23393559
DOI: 10.1371/journal.pone.0054831
PMCID: PMC3564922

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Influence of the serotonin transporter 5HTTLPR polymorphism on symptom severity in irritable bowel syndrome.PMID 23393559Read ↗

The serotonin transporter gene polymorphism (5-HTTLPR) and irritable bowel syndrome: a meta-analysis of 25 studies.Semantic proximity Read ↗

5-HTTLPR and STin2 polymorphisms in the serotonin transporter gene and irritable bowel syndrome: effect of bowel habit and sexSemantic proximity Read ↗

Association study of serotonin transporter SLC6A4 gene with Chinese Han irritable bowel syndrome.Semantic proximity Read ↗

A serotonin transporter gene (SLC6A4) polymorphism is associated with reduced risk of irritable bowel syndrome in American and Asian population: a meta-analysis.Semantic proximity Read ↗

Serotonin transporter gene polymorphisms in Southwestern Iranian patients with irritable bowel syndrome.Semantic proximity Read ↗

Serotonin Transporter Gene Polymorphism in Irritable Bowel SyndromeSemantic proximity Read ↗

Relationship of SERT polymorphisms to depressive and anxiety symptoms in irritable bowel syndrome.Semantic proximity Read ↗

The serotonin transporter polymorphism rs25531 is associated with irritable bowel syndrome.Semantic proximity Read ↗

[Serotonin transporter gene polymorphism in irritable bowel syndrome].Semantic proximity Read ↗

Serotonin transporter gene promoter region polymorphisms and serotonin transporter expression in the colonic mucosa of irritable bowel syndrome patients.Semantic proximity Read ↗

Association of the 1438G/A and 102T/C Polymorphism of the 5-HT2A Receptor Gene With Irritable Bowel Syndrome 5-HT2A Gene Polymorphism in Irritable Bowel SyndromeSemantic proximity Read ↗

Serotonin transporter promoter variant: Analysis in Indian IBS patients and control population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.