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Article

Alterations in expression of p11 and SERT in mucosal biopsy specimens of patients with irritable bowel syndrome.

Gastroenterology - 1 Jan 2007

Camilleri Michael, Andrews Christopher N, Bharucha Adil E, Carlson Paula J, Ferber Irene, Stephens Debra, Smyrk Thomas C, Urrutia Raul, Aerssens Jeroen, Thielemans Leen, Göhlmann Hinrich, van den Wyngaert Ilse, Coulie Bernard

Abstract excerpt

BACKGROUND & AIMS: The pathophysiology of irritable bowel syndrome (IBS) remains enigmatic; abnormalities in serotonin metabolism have been implicated. Two proteins that influence the function of serotonin and serotonergic receptors are serotonin transporter protein (SERT or soluble carrier protein, SLC6A4) and p11 (S-100A10, or calpactin I light chain). Both proteins are reported to be associated with...

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Identifiers

PMID: 17241856
DOI: 10.1053/j.gastro.2006.11.020
PMCID: PMC2474784

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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