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Article

PPP2R1A mutation status as a predictive and prognostic factor in molecularly characterized endometrial carcinoma: a cohort study.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Sept 2025

Khatun Masuma, Pasanen Annukka, Kanerva Anna, Koivisto-Korander Riitta, Tuomi Taru, Bützow Ralf, Loukovaara Mikko

Abstract excerpt

OBJECTIVE: To evaluate associations of mutations in PPP2R1A, encoding the Aα subunit of protein phosphatase 2A (PP2A), with molecular sub-groups, clinicopathologic factors, predictive/prognostic biomarkers, and survival in endometrial carcinoma. METHODS: This retrospective study used sequencing, immunohistochemistry, and dual-color chromogenic in situ hybridization to assess PPP2R1A mutations, molecular...

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Identifiers

PMID: 40467434
DOI: 10.1016/j.ijgc.2025.101934

Genes

PPP2R1A

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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