Article
Massively-parallel sequencing of genes on a single chromosome: a comparison of solution hybrid selection and flow sorting.
BMC genomics - 15 Apr 2013
Teer Jamie K, Johnston Jennifer J, Anzick Sarah L, Pineda Marbin, Stone Gary, Meltzer Paul S, Mullikin James C, Biesecker Leslie G
Abstract excerpt
BACKGROUND: Targeted capture, combined with massively-parallel sequencing, is a powerful technique that allows investigation of specific portions of the genome for less cost than whole genome sequencing. Several methods have been developed, and improvements have resulted in commercial products targeting the human or mouse exonic regions (the exome). In some cases it is desirable to custom-target other regions of...
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