Article
Systematic comparison of three genomic enrichment methods for massively parallel DNA sequencing.
Genome research - 1 Oct 2010
Teer Jamie K, Bonnycastle Lori L, Chines Peter S, Hansen Nancy F, Aoyama Natsuyo, Swift Amy J, Abaan Hatice Ozel, Albert Thomas J, Margulies Elliott H, Green Eric D, Collins Francis S, Mullikin James C, Biesecker Leslie G
Abstract excerpt
Massively parallel DNA sequencing technologies have greatly increased our ability to generate large amounts of sequencing data at a rapid pace. Several methods have been developed to enrich for genomic regions of interest for targeted sequencing. We have compared three of these methods: Molecular Inversion Probes (MIP), Solution Hybrid Selection (SHS), and Microarray-based Genomic Selection (MGS). Using HapMap...
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