Article
Genome-wide Target Enrichment-aided Chip Design: a 66 K SNP Chip for Cashmere Goat.
Scientific reports - 17 Aug 2017
Qiao Xian, Su Rui, Wang Yang, Wang Ruijun, Yang Ting, Li Xiaokai, Chen Wei, He Shiyang, Jiang Yu, Xu Qiwu, Wan Wenting, Zhang Yaolei, Zhang Wenguang, Chen Jiang, Liu Bin, Liu Xin, Fan Yixing, Chen Duoyuan, Jiang Huaizhi, Fang Dongming, Liu Zhihong, Wang Xiaowen, Zhang Yanjun, Mao Danqing, Wang Zhiying, Di Ran, Zhao Qianjun, Zhong Tao, Yang Huanming, Wang Jian, Wang Wen, Dong Yang, Chen Xiaoli, Xu Xun, Li Jinquan
Abstract excerpt
Compared with the commercially available single nucleotide polymorphism (SNP) chip based on the Bead Chip technology, the solution hybrid selection (SHS)-based target enrichment SNP chip is not only design-flexible, but also cost-effective for genotype sequencing. In this study, we propose to design an animal SNP chip using the SHS-based target enrichment strategy for the first time. As an update to the...
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