Article

Single Nucleotide Polymorphism (SNP) and Antibody-based Cell Sorting (SNACS): A tool for demultiplexing single-cell DNA sequencing data

2024-02-10

Abstract excerpt

<h4>Motivation</h4> Recently, single-cell DNA sequencing (scDNA-seq) and multi-modal profiling with the addition of cell-surface antibodies (scDAb-seq) have provided key insights into cancer heterogeneity. Scaling these technologies across large patient cohorts, however, is cost and time prohibitive. Multiplexing, in which cells from unique patients are pooled into a single experiment, offers a possible solution....

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Literature Corpus work: 900a8321-9655-52b0-a53d-5c1349606352
DOI: 10.1101/2024.02.07.579345

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