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Article

Whole exome capture in solution with 3 Gbp of data.

Genome biology - 1 Jan 2010

Bainbridge Matthew N, Wang Min, Burgess Daniel L, Kovar Christie, Rodesch Matthew J, D'Ascenzo Mark, Kitzman Jacob, Wu Yuan-Qing, Newsham Irene, Richmond Todd A, Jeddeloh Jeffrey A, Muzny Donna, Albert Thomas J, Gibbs Richard A

Abstract excerpt

We have developed a solution-based method for targeted DNA capture-sequencing that is directed to the complete human exome. Using this approach allows the discovery of greater than 95% of all expected heterozygous singe base variants, requires as little as 3 Gbp of raw sequence data and constitut...

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Identifiers

PMID: 20565776
DOI: 10.1186/gb-2010-11-6-r62
PMCID: PMC2911110

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20565776-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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